Modulation of Pseudomonas aeruginosa adherence to the corneal surface by mucus
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چکیده
منابع مشابه
Adherence of Pseudomonas aeruginosa to tracheal epithelium.
Adherence of mucoid and nonmucoid strains of Pseudomonas aeruginosa to tracheal epithelium was studied with a perfused-trachea model. The species specificity of adherence was studied by infecting tracheas from hamsters, guinea pigs, or mice. Perfused tracheas from hamsters were infected with strains of P. aeruginosa in the presence of various sugars, lectins, cations, or charged polymers. Adher...
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Pseudomonas aeruginosa is an opportunistic organism, which frequently colonizes the respiratory tract of patients with impaired host defence. In cystic fibrosis (CF) patients, this pathogen causes a progressive destructive bronchitis and bronchiolitis and is responsible for high mortality. Normal respiratory epithelium is protected against bacteria via mucus and mucociliary clearance. Alteratio...
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UNLABELLED Adaptation of bacterial pathogens to a host can lead to the selection and accumulation of specific mutations in their genomes with profound effects on the overall physiology and virulence of the organisms. The opportunistic pathogen Pseudomonas aeruginosa is capable of colonizing the respiratory tract of individuals with cystic fibrosis (CF), where it undergoes evolution to optimize ...
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background and objectives: bacterial resistance to conventional antibiotics has become a widespread public health prob- lem. the aim of this study was to investigate the influence of zinc oxide nanoparticles (zno nps) on the antibacterial activity of several conventional antibiotics against pseudomonas aeruginosa. materials and methods: zno nps were prepared by solvothermal method and dispersed...
متن کاملExtended contact lens wear enhances Pseudomonas aeruginosa adherence to human corneal epithelium.
Extended wear of soft contact lenses is associated with an increased risk of Pseudomonas aeruginosa infection of the cornea. To assess the role of bacterial adherence in the pathogenesis of these infections, superficial corneal epithelial cells and leukocytes from ten patients who use extended-wear soft lenses and ten control eyes were compared for their propensity to attach P. aeruginosa in vi...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1994
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.62.5.1799-1804.1994